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生命科学系の論文のサマリーを読んでいきます。また時々趣味の読書の感想も書いていきます。

HSC

CCR5 Signaling Promotes Murine and Human Hematopoietic Regeneration following Ionizing Radiation

Available online 30 May 2019 In Press, Corrected ProofWhat are Corrected Proof articles? Article CCR5 Signaling Promotes Murine and Human Hematopoietic Regeneration following Ionizing Radiation Author links open overlay panelSadhna O.Pirya…

Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation

Letter | Published: 29 May 2019 Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation Adam C. Wilkinson, Reiko Ishida, Misako Kikuchi, Kazuhiro Sudo, Maiko Morita, Ralph Valentine Crisostomo, Ryo Yamamo…

Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia.

Cell. 2018 May 31;173(6):1439-1453.e19. doi: 10.1016/j.cell.2018.05.013. Epub 2018 May 31. Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia. Kim MY1, Yu KR2, Kenderian S…

Effect of developmental stage of HSC and recipient on transplant outcomes.

Dev Cell. 2014 Jun 9;29(5):621-628. doi: 10.1016/j.devcel.2014.04.013. Effect of developmental stage of HSC and recipient on transplant outcomes. Arora N1, Wenzel PL2, McKinney-Freeman SL3, Ross SJ1, Kim PG1, Chou SS1, Yoshimoto M4, Yoder …

Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia.

Cancer Cell. 2008 Jun;13(6):483-95. doi: 10.1016/j.ccr.2008.04.020. Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia. Wei J1, Wunderlich M, Fox C, Alvarez S, Cigudosa JC, Wilhelm JS, Zheng Y, Cancelas JA, Gu Y,…

Age-Associated Differences in Hematopoietic Stem and Progenitor Cells of Mice

Comp Med. 2017 Feb; 67(1): 22–27. Published online 2017 Feb. PMCID: PMC5310621 Age-Associated Differences in Hematopoietic Stem and Progenitor Cells of Mice Samanta Gasco,1 Amaya Rando,1 Pilar Zaragoza,1 Alberto García-Redondo,2 Ana C Calv…

Lineage switch in childhood acute leukemia: an unusual event with poor outcome.

Am J Hematol. 2012 Sep;87(9):890-7. doi: 10.1002/ajh.23266. Epub 2012 Jun 8. Lineage switch in childhood acute leukemia: an unusual event with poor outcome. Rossi JG1, Bernasconi AR, Alonso CN, Rubio PL, Gallego MS, Carrara CA, Guitter MR,…

Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing.

Blood. 2012 Mar 15;119(11):2500-9. doi: 10.1182/blood-2011-11-391730. Epub 2012 Jan 30. Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing. Ergen AV1, Boles NC, Goodell MA. 造血幹細胞(HSC)は年齢により劇的に…